The purpose of the present study is to analyze the effect of quantum leadership on organizational excellence with the mediating role of organizational knowledge management and quantum skills. This is an applied-based research and a survey analytic causal-descriptive one that was conducted. This research is also part of the cross-sectional research. The questionnaire was used for data collection and its validity and reliability were confirmed. The statistical population of this study consisted of all 3659 employees of Mega Motor Company. A sample size of 347 persons was selected and studied according to Morgan's table by simple random sampling. Data analysis was also done through structural equation modeling methods. Two hypotheses were presented for the present study after testing, the results of the present study showed that quantum leadership dimensions have a significant effect on the organizational excellence of mega Motor Companies with mediating role of knowledge management. The results also showed that quantum leadership dimensions have a significant effect on the organizational excellence of Mega Motor with the mediating role of quantum skills. Since quantum leadership has a significant impact on organizational excellence with the mediating role of organizational knowledge management and quantum skills, therefore, quantum skills and strategic knowledge management can be improved in enhancing corporate leadership level.